Cellular Immunology: Infection Immunity, Cancer Immunology, Inflamation and Immune regulation
Dr. Subhasis Chattopadhyay
School of Biological Sciences
National Institute of Science Education and Research
Via- Jatni, District: Khurda,
Pin code- 752050
Fax: +91 (674) 2304070
Cellular and Immunological investigation towards altered host cell responses
The fundamental consequences of cellular responses associated to altered physiological processes during infection, cancer and/or tumor progression, inflammation and immunogenic responses in various cases of altered host cell functions and phenotypes are the prime interest of our ongoing research.
We have been working in the field of host cell responses and cellular immunology with special interest of ongoing immune-regulatory responses, cellular function and phenotypes associated to Cell mediated immunity (CMI) of T cells and accessory antigen presenting cells. Currently, we have major interest groups within NISER and also with external collaboration, where we are investigating functional expression of Toll like receptor (TLR) and Transient Receptor Potential Vanilloid (TRPV) Channels in cell mediated immunity (CMI), analyzing cellular and immunological response(s) of host cells during experimental Chikungunya virus (CHIKV) infection along with anti-cancer immunity as major projects.
In brief, our research focuses to dissect out the important roles of cellular and immunological aspects to decipher the cellular pathways, strategies associated to altered host cell responses for an ongoing infection, tumor progression, inflammation-immunity and immuno-regulatory processes associated to diseases biology in different contexts of cellular responses. Research with cell lines, primary cells, animal model and also with the human blood samples from normal donors and patients with due consents and National guide lines are the prime components for such experimental studies. Such understanding will be helpful towards designing immuno-therapeutic strategies to control various diseases.
Courses taught in NISER (between 2009-2015):
Animal Physiology; Cell Biology; Cancer Biology; Immunology, Advanced Immunology; Immune regulation and Infection immunity
© 2016-17 National Institute of Science Education and Research Bhubaneswar, All Rights Reserved.