Tumour Angiogenesis Regulation and Cancer Genetics
Kumar D, Hassan MK, Pattnaik N, Mohapatra N, Dixit M, Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers, PLoS One. 2017 Oct 26;12(10):e0186977. [Pubmed]
Tiwari A, Pattnaik N, Mohanty Jaiswal A, Dixit M, Increased FSHD region gene1 expression reduces in vitro cell migration, invasion, and angiogenesis, ex vivo supported by reduced expression in tumors, Biosci Rep. 2017 Oct 27;37(5). pii: BSR20171062. [Pubmed]
Tiwari A, Mukherjee B, Dixit M, MicroRNA Key to Angiogenesis Regulation: miRNA Biology and Therapy, Curr Cancer Drug Targets. 2017 Jun 30. [Pubmed]
Hansda AK, Tiwari A, Dixit M, Current status and future prospect of FSHD region gene 1, J Biosci. 2017 Jun;42(2):345-353. [Pubmed]
Dr. Dixit's research interest is to understand the genetics and molecular biology of various human genetic diseases, especially cancer.
During her postdoc in University of Utah, she worked on angiogenesis in eye disease and developed interest in this subject. Abnormal growth of new blood vessels plays an important role in many diseases, including cancer. To treat cancer, various potential anti-angiogenesis drugs have been tested with limited success. Blocking just one regulatory pathway may not be enough. To date, all these angiogenic-switch regulatory molecules and their mechanism are not known. In order to do that, her research group is interested towards the validation and elucidation of the molecular mechanism of putative angiogenic regulators. Moreover, her group is also working towards the ilucidation of genetic predisposition for Gallbladder cancer in the population of Odisha.
Dr. Dixit regularly offer two theory and two practical courses in odd or even semeter.
Tel 0674-2304195, 0674-2304196
School of Biological Sciences, National Institute of Science Education and Research
© 2018 National Institute of Science Education and Research Bhubaneswar, All Rights Reserved.