Pharmaceutical Biology; Structural Bioinformatics; Biotechnology
List of Publications (from Pubmed)
Rational drug discovery and development requires a streamlined interdisciplinary effort from researchers working in a specialised area. From active collaboration, drug discovery process can be and has been shortened to a great extent by addressing bottlenecks in drug discovery (such as high-thoroughput screening, specificity and chemoresistance). Our research efforts focus on some of these unaddressed questions that would potentially contribute in chemotherapy. On the other hand, while novel compounds are in great demand to be translated as a drug, nevertheless, it is hard to predict its activity (anti-cancer, anti-diabetic or as any chemotherapeutic) in the first instance. Therefore, as a pre-screening step we first try to understand the cellular response of the ligand or its affinity to a molecular target by applying different computational and experimental methods (biochemical, molecular biology, microscopy or on cell lines).
The following are the areas presently we focus on:
Interdisciplinary approaches in development of cancer therapeutics
Understanding cellular reponse to different ligands deriving its implications
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